Computed tomography as a risk factor of cancer among the population of the nuclear city of Ozyorsk

Exposure to ionizing radiation resulted from computed tomography (CT) examinations concerns a risk associated with potential radiation-induced cancers. Widespread use of this diagnostic method during the last decades has led significant increase collective dose world’s population. Minor restrictions for X-ray procedures involve considerable “beneficial” exposure burden among CT-examined patients. Assessment possible consequences became necessary in order manage risks terms “benefit-harm” control. Retrospective epidemiological study been performed using cohort individuals exposed CT. The source information was “CT Register” database which contains medical and dosimetric data on population nuclear city Ozyorsk, including several factors such as gender, age at exposure, cancer anamnesis contact occupational radiation. Risk calculation conditional logistic regression. A hypothesis increasing chances developing malignant neoplasm depending number recurrent CT lifetime, taking into account confounders impact reverse causation tested. relation between subsequent (OR 1.01-1.10) can be confirmed (1-alpha) 90%, indicates probable radiogenic component carcinogenic risk. Further investigation expanded follow-up period will facilitate accounting unrealized cases long latency improve results study.